Structure of PDB 8eui Chain j Binding Site BS02

Receptor Information

>8eui Chain j (length=83) Species: 4896 (Schizosaccharomyces pombe)

TKGTQSFGMRHNKSHTICRRCGKRSFHIQKSTCACCGYPAAKTRSYNWGA
KAKRRRTTGTGRMSYLKKVHRSFKNGFRSGKPA

Ligand information

>8eui Chain 2 (length=158)

aaaacuuucagcaacggaucucuuggcucucgcaucgaugaagaacgcag
cgaaaugcgauacguaaugugaauugcagaauuccgugaaucaucgaauc
uuugaacgcacauugcgccuuuggguucuaccaaaggcaugccuguuuga
gugucauu

..........................................<<<<<<.<
<.....>>>.....(.<<<......>>..............>>>..)...
>>>....<<.....>><<<<<<<<......>>>>>>>>............
........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8eui Chromatin localization of nucleophosmin organizes ribosome biogenesis.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): R20 R21 C22 G23 I29 T59 G60 G62 R63 M64 Y66 L67 K68 R72 F74 N76 F78 R79 G81 K82 P83
• Binding residue (residue number reindexed from 1): R19 R20 C21 G22 I28 T58 G59 G61 R62 M63 Y65 L66 K67 R71 F73 N75 F77 R78 G80 K81 P82

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008270 zinc ion binding
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8eui, PDBe:8eui, PDBj:8eui
• PDBsum: 8eui
• PubMed: 36423630
• UniProt: P05733|RL37B_SCHPO Large ribosomal subunit protein eL37B (Gene Name=rpl3702)