Structure of PDB 8etj Chain j Binding Site BS02

Receptor Information

>8etj Chain j (length=71) Species: 4896 (Schizosaccharomyces pombe)

KSHTICRRCGKRSFHIQKSTCACCGYPAAKTRSYNWGAKAKRRRTTGTGR
MSYLKKVHRSFKNGFRSGKPA

Ligand information

>8etj Chain 2 (length=144)

aaaacuuucagcaacggaucucuuggcucucgcaucgaugaagaacgcag
cgaaaugcgauacguaaugugaauugcagaagaaucaucgaaucuuugaa
cgcacgcgccuuugggaccaaaggcaugccuguuugagugucau

..........................................<<<<<<<<
<....>>>>.....<.<<<......>>........>>>..>...>>>...
.<<..>><<<<<<<<..>>>>>>>>...................

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8etj Chromatin localization of nucleophosmin organizes ribosome biogenesis.
• Resolution: 3.2 Å
• Binding residue (original residue number in PDB): R20 R21 T59 G62 R63 M64 Y66 L67 R72 F74 R79 G81 P83
• Binding residue (residue number reindexed from 1): R7 R8 T46 G49 R50 M51 Y53 L54 R59 F61 R66 G68 P70

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0008270 zinc ion binding
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8etj, PDBe:8etj, PDBj:8etj
• PDBsum: 8etj
• PubMed: 36423630
• UniProt: P05733|RL37B_SCHPO Large ribosomal subunit protein eL37B (Gene Name=rpl3702)