Structure of PDB 7nwi Chain j Binding Site BS02

Receptor Information
>7nwi Chain j (length=86) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK
Ligand information
>7nwi Chain 8 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<<..>>><<<<<<<<.......>>>>>>>>..............
......
Receptor-Ligand Complex Structure
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PDB7nwi Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Resolution3.13 Å
Binding residue
(original residue number in PDB)		R20 R21 G23 T59 G62 R63 M64 H66 Y71 R72 F74 H76 R79 E80 G81 T82 T83 P84
Binding residue
(residue number reindexed from 1)		R19 R20 G22 T58 G61 R62 M63 H65 Y70 R71 F73 H75 R78 E79 G80 T81 T82 P83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nwi, PDBe:7nwi, PDBj:7nwi
PDBsum7nwi
PubMed34157102
UniProtU3KPD5|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)

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