Structure of PDB 7nhl Chain j Binding Site BS02

Receptor Information
>7nhl Chain j (length=127) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFD
VTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGL
LTRDPRMKERKKPGLKAARRSPQFSKR
Ligand information
>7nhl Chain a (length=1538) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaauaca
ugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcggcg
gacgggugaguaacacguggauaaccuaccuauaagacugggauaacuuc
gggaaaccguagcuaauaccggauaauauuuugaaccgcaugguucaaaa
gugaaagacggucuugcugucacuuauagauggauccgcgcugcauuagc
uaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccuga
gagggugaucggccacacuggaacugagacacgguccagacuccuacggg
aggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagcaac
gccgcgugagugaugaaggucuucggaucguaaaacucuguuauuaggga
agaacauauguguaaguaacugugcacaucuugacgguaccuaaucagaa
agccacggcuaacuacgugccagcagccgcgguaauacguagguggcaag
cguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaagu
cugaugugaaagcccacggcucaaccguggagggucauuggaaacuggaa
aacuugagugcagaagaggaaaguggaauuccauguguagcggugaaaug
cgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucugua
acugacgcugaugugcgaaagcguggggaucaaacaggauuagauacccu
gguaguccacgccguaaacgaugagugcuaaguguuaggggguuucccgc
cccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacgac
cgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugga
gcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugaca
uccuuugacaacucuagagauagagccuuccggacaaagugacagguggu
gcaugguugucgucagcucgugucgugagauguuggguuaagucccgcaa
cgagcgcaacccuuaagcuuaguugccaucauuaaguugggcacucuaag
uugacugccggugacaaaccggaggaagguggggaugacgucaaaucauc
augccccuuaugauuugggcuacacacgugcuacaauggacaauacaaag
ggcagcgaaaccgcgaggucaagcaaaucccauaaaguuguucucaguuc
ggauuguagucugcaacucgacuacaugaagcuggaaucgcuaguaaucg
uagaucagcaugcuacggugaauacguucccgggucuuguacacaccgcc
cgucacaccacgagaguuuguaacacccgaagccgguggaguaaccuuuu
aggagcuagccgucgaaggugggacaaaugauuggggugaagucguaaca
agguagccguaucggaaggugcggcuggaucaccuccu
...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<<...<<<.........>.>>...>>>>.>>>>>.
.....<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<.<
<<....>>>.>>......>>>>......<<<.<<<<<<..>>>>>>>>>.
......<<<<<<...>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<
<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<..
..>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>
>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>
>>>>>..<<<<......<<<<....>>>>.....>>>>...<<<<<<<..
.....<.<<<<<<<........>>>>>>>.>........>>>>>>...>.
.<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>
>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<<<
<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>>>
>>>...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>
>......>>>>>>>.>..........<<....>>.>>>>>>>..>>>>>.
>>>...>>>..>>>>>....<<<<<<<...<...<<<<.<.....>.>>>
>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<<<.....>>
>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<
<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<
<<<<<<<<<......<<........>>..........<<<<<<<......
<<<<<<.....<<<<<....>>>>>..........>>>>.>>.<<<.<<<
..<<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>
>>>>>.....<<<<.<<<<<<<..<<<..<<......>>>>>...>>>>>
>>.....<<<<<.....>>>>>........>>>>.........>>>...>
>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<
<<..<<...<<<....>>>...>>....>>>.....>>>>>>>......<
..<.<<<<<<<........>>>>>>>>...>.....>>>>>>....<<<<
<<<.........>>>>>>>......>>...>>>>>>>>>>.>>....<..
<<.<.<<<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<<...
>>>.>>>.>>>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.
....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB7nhl Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
R9 R13 R14 K15 V18 R20 R22 R35 N68 H70 G71 G72 G73 F74 T75 Q77 R97 K101 T107 R108 R111 M112 K113 R115 K116 K117 G119 K121 R124 R125 S126 P127 Q128 F129 R132
Binding residue
(residue number reindexed from 1)
R4 R8 R9 K10 V13 R15 R17 R30 N63 H65 G66 G67 G68 F69 T70 Q72 R92 K96 T102 R103 R106 M107 K108 R110 K111 K112 G114 K116 R119 R120 S121 P122 Q123 F124 R127
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7nhl, PDBe:7nhl, PDBj:7nhl
PDBsum7nhl
PubMed34117249
UniProtQ2FW39|RS9_STAA8 Small ribosomal subunit protein uS9 (Gene Name=rpsI)

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