Structure of PDB 5sva Chain j Binding Site BS02

Receptor Information
>5sva Chain j (length=180) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGIVPTLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPK
TTALIFASGKMVVTGAKSEDDSKLASRKYARIIQKIGFAAKFTDFKIQNI
VGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIYRMVKPKIVLLIFVSG
KIVLTGAKQREEIYQAFEAIYPVLSEFRKM
Ligand information
>5sva Chain m (length=62) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgtatgtacaacacacatcggaggtgaatcgaacgttccatagctattat
atacacagcata
Receptor-Ligand Complex Structure
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PDB5sva Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex.
Resolution15.3 Å
Binding residue
(original residue number in PDB)		Q68 N69 V71 E93 K97 R98 F99 A100 A101 I103 R105 K110 T112 L114 F116 T124 G125 K127 F207 S209 K211
Binding residue
(residue number reindexed from 1)		Q8 N9 V11 E33 K37 R38 F39 A40 A41 I43 R45 K50 T52 L54 F56 T64 G65 K67 F147 S149 K151
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0001016 RNA polymerase III transcription regulatory region sequence-specific DNA binding
GO:0001092 TFIIA-class transcription factor complex binding
GO:0001179 RNA polymerase I general transcription initiation factor binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0008301 DNA binding, bending
GO:0016251 RNA polymerase II general transcription initiation factor activity
GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding
GO:0097718 disordered domain specific binding
GO:0140297 DNA-binding transcription factor binding
Biological Process
GO:0001188 RNA polymerase I preinitiation complex assembly
GO:0006352 DNA-templated transcription initiation
GO:0006359 regulation of transcription by RNA polymerase III
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0045892 negative regulation of DNA-templated transcription
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051123 RNA polymerase II preinitiation complex assembly
GO:0070898 RNA polymerase III preinitiation complex assembly
Cellular Component
GO:0000126 transcription factor TFIIIB complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005669 transcription factor TFIID complex
GO:0005672 transcription factor TFIIA complex
GO:0032991 protein-containing complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5sva, PDBe:5sva, PDBj:5sva
PDBsum5sva
PubMed27610567
UniProtP13393|TBP_YEAST TATA-box-binding protein (Gene Name=SPT15)

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