Structure of PDB 5lzx Chain j Binding Site BS02

Receptor Information

>5lzx Chain j (length=86) Species: 9986 (Oryctolagus cuniculus)

TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK

Ligand information

>5lzx Chain 8 (length=151)

cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
u

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>........>>>..>...>>>....
<<<..>>><<<<<<<<.......>>>>>>>>...................
.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5lzx Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
• Resolution: 3.67 Å
• Binding residue (original residue number in PDB): R20 R21 Y39 K42 N57 T59 G62 R63 M64 R65 H66 L67 V70 Y71 R72 F74 H76 R79 G81 T82 T83 P84 K85 P86 K87
• Binding residue (residue number reindexed from 1): R19 R20 Y38 K41 N56 T58 G61 R62 M63 R64 H65 L66 V69 Y70 R71 F73 H75 R78 G80 T81 T82 P83 K84 P85 K86

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5lzx, PDBe:5lzx, PDBj:5lzx
• PDBsum: 5lzx
• PubMed: 27863242
• UniProt: U3KPD5|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)