Structure of PDB 8bpo Chain i2 Binding Site BS02

Receptor Information

>8bpo Chain i2 (length=86) Species: 9986 (Oryctolagus cuniculus)

TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK

Ligand information

>8bpo Chain C1 (length=151)

cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
u

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>........>>>..>...>>>....
<<<..>>><<<<<<<<.......>>>>>>>>...................
.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8bpo Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): R20 R21 Y39 T58 T59 G62 R63 M64 R65 H66 L67 K68 R72 F74 H76 R79 E80 G81 T82 P84 K87
• Binding residue (residue number reindexed from 1): R19 R20 Y38 T57 T58 G61 R62 M63 R64 H65 L66 K67 R71 F73 H75 R78 E79 G80 T81 P83 K86

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8bpo, PDBe:8bpo, PDBj:8bpo
• PDBsum: 8bpo
• PubMed: 37295431
• UniProt: U3KPD5|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)