Structure of PDB 7ls1 Chain i2 Binding Site BS02

Receptor Information

>7ls1 Chain i2 (length=103) Species: 10090 (Mus musculus)

VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQ
TKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKG
QVI

Ligand information

>7ls1 Chain n2 (length=75)

agcagaguggcgcagcggaagcgugcugggcccauaacccagaggucgau
ggaucgaaaccauccucugcuacca

<<<<<<<..<<...........>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7ls1 Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
• Resolution: 3.3 Å
• Binding residue (original residue number in PDB): K38 Y41 K53 P54 I55 F56
• Binding residue (residue number reindexed from 1): K37 Y40 K52 P53 I54 F55

Gene Ontology

Molecular Function

• GO:0003674 molecular_function
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0008150 biological_process
• GO:0140236 translation at presynapse
• GO:0140242 translation at postsynapse

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:0045202 synapse
• GO:0098793 presynapse
• GO:0098794 postsynapse
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7ls1, PDBe:7ls1, PDBj:7ls1
• PDBsum: 7ls1
• PubMed: 34815424
• UniProt: P83882|RL36A_MOUSE Large ribosomal subunit protein eL42 (Gene Name=Rpl36a)