Structure of PDB 8qfd Chain h Binding Site BS02

Receptor Information
>8qfd Chain h (length=120) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKS
IARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEENLK
TKKQQRKERLYPLRKYAVKA
Ligand information
>8qfd Chain 8 (length=144) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagcu
agcugcgagaauuaaugugaauugcaggcgaucaucgacacuucgaacgc
acuugcggccccgggcccggggcuacgccugucugagcgucgcu
........................................<<<<<<<<<.
...>>>>.....<.<<<......>>.......>>>..>...>>>....<<
....>><<<<<<<<<>>>>>>>>>....................
Receptor-Ligand Complex Structure
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PDB8qfd The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons
Resolution2.2 Å
Binding residue
(original residue number in PDB)		R7 K35 S45 R48 R51 K52 A55 R56 L58 T59 N62 Q63 K66 K86 R89 R92
Binding residue
(residue number reindexed from 1)		R4 K32 S42 R45 R48 K49 A52 R53 L55 T56 N59 Q60 K63 K83 R86 R89
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qfd, PDBe:8qfd, PDBj:8qfd
PDBsum8qfd
PubMed38383789
UniProtP42766|RL35_HUMAN Large ribosomal subunit protein uL29 (Gene Name=RPL35)

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