Structure of PDB 8bvw Chain h Binding Site BS02

Receptor Information
>8bvw Chain h (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>8bvw Chain T (length=206) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcggatgtatatatctgacacgtgcctggagactagggagtaatcccctt
ggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctag
agctgtctacgaccaattgagcggcctcggcaccgggattctcgatcagc
gatgcggaagagagtgaggacgaacgcgcccccacccccttttatagccc
cccttc
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8bvw Structural basis of transcription reduction by a promoter-proximal +1 nucleosome.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		K32 R34 Y43 I55 S56 S57 R87 S88 T89
Binding residue
(residue number reindexed from 1)		K1 R3 Y12 I24 S25 S26 R56 S57 T58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8bvw, PDBe:8bvw, PDBj:8bvw
PDBsum8bvw
PubMed37148879
UniProtP02281|H2B11_XENLA Histone H2B 1.1

[Back to BioLiP]