Structure of PDB 5t2a Chain h Binding Site BS02

Receptor Information
>5t2a Chain h (length=124) Species: 5661 (Leishmania donovani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SCPRVQYRRRMHYATRGNRMKMVRTPGNKLVMQKRAKRSQGIHTPWVLGH
KRLGGTKALRHIDARLASRHEKSVSRAYGGVLSHDQVRDRVVRAFLVEEQ
RIVKQALKEHSKMKLSHKRTANKK
Ligand information
>5t2a Chain B (length=1064) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccaacugcagaccguacucaucaccgcaucagguccccaagcauagaau
gcucugguacauagagaaagguacacucagggaagucggcaaaauagaug
cguaaguucgcaagaagcauuggcucugagggcaauugccaacucagaac
ugcuuacggcggggaauccaacuguauaauuaaaacauagguuugugaug
cauccaagugguguauaucgcaaacugauuucugcccagugcucugaaug
ucaacgugacgagauucaccgacgcgcggguaaacggcgggaguaacuau
gacucucuuaagguagccaaaugccucgucuuccaauuagagacgcgcau
gaauggauuaaugagauucccucugucccgaguuacuaucuagcgaaacg
acagucaagggaacggacuugaagggcuaagcggggaaagaagacccugu
ugaguuugacuccagucuggcucugugcggcgacguugcuucacuuaucg
aaugaagagaccaaugggcgugcuguaaacugaaccaacggguccggagu
cuuguuucgagacaucugccagauggggaguuuggcuggggcggcauauc
uguuacacgacaacgcagguguccuaaggcgagcucagugggaacagaaa
ucucacguagaacacaagcguaaaagcuugcuugauuaacgauuuccagu
acgaaucgagacugcgaaagcaaggccagcgauccuuugcgaagaauagg
aaauaugaacaaaucauaccagaggugucagaauaauuaccacagggaua
acuggcuuguggcggccaagcguucauagcgacgucgcuuuuugauccuu
cgaugucggcucuuccuaaccuagcgccgcagaagacgcuaaggguugga
uuguucacccacugacagggaacgugagcuggguuuagaccgucgugaga
cagguugguuuuacccuacuuagcuggaaauugcgagaaaagauuauccg
cgcaaagcggaggcaguccgucugggucugccguucgguggcaugugcuu
ggcgcugccaucuc
........................<<......>>......<<<<.....>
>>>........<<<<....<<<<.<<<<.<<.........<.....<<<<
<...............>>>>><<.<<<<<<<<<<..>>>>..>>>>>>.>
>..........<<<<<<<<<..<<<.........>>>..<<<<<<<....
<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.....<
<....<<<<......>>>>....>>..>>>>..>>>>><<<<<<......
.>>>>>>........<...........<<<<<.......>>>>>.....>
.....>>....>>.>>>>>>>..>..>>.>>>>>>>>.>>>>........
....<<<<<........>>>>>..<<<<<<<..<<<.<<......<<<<.
<<<<<<..<<<<<.<<<<<<<...<<<.<<<<<..>>>>>.>>>...<<<
<<.....<<<<...........................<<<..>>>..>>
>>...>>>>>.......>>>>>>>..>>>>>...<<<.....>>>..<<<
<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......
>>>>>>.....<<......>>....>>>>>>>...<<...<<<<<.....
..>>>>>..>>.<<<....>>>.>>........<<<<<<...........
...<<<<.......>>>>.>>>>>>.........>>>>..>>>>>>....
...<<.<.<.<<<<<<...<<.......>>...>>>>>>...>>.>.>..
.....<<<<<.<<<<<<..<<<<<<<.<......>.>>>>..>>>.<<<.
........>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>
>.>>>>....>>..>>>.>>>>>>>......................<<<
<.....>>>>.<<<<<<<<....>>>.>>>>>....<<<<<<<..<....
...>.>>>>>>>..
Receptor-Ligand Complex Structure
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PDB5t2a Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		C3 R5 V6 Y8 H13 Y14 R91 R94 A95 R102 K105 K109
Binding residue
(residue number reindexed from 1)		C2 R4 V5 Y7 H12 Y13 R90 R93 A94 R101 K104 K108
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5t2a, PDBe:5t2a, PDBj:5t2a
PDBsum5t2a
PubMed27752045
UniProtA0A3Q8IHK2

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