Structure of PDB 5lzx Chain h Binding Site BS02

Receptor Information

>5lzx Chain h (length=122) Species: 9986 (Oryctolagus cuniculus)

AKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVR
KSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEES
LKTKKQQRKERLYPLRKYAVKA

Ligand information

>5lzx Chain 8 (length=151)

cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
u

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....>>>>.....<.<<<......>>........>>>..>...>>>....
<<<..>>><<<<<<<<.......>>>>>>>>...................
.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5lzx Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
• Resolution: 3.67 Å
• Binding residue (original residue number in PDB): K5 R7 R10 L44 S45 R48 R51 K52 A55 R56 L58 T59 N62 Q63 K66 R70 L81 R84 K86 T88 R89 R92
• Binding residue (residue number reindexed from 1): K4 R6 R9 L43 S44 R47 R50 K51 A54 R55 L57 T58 N61 Q62 K65 R69 L80 R83 K85 T87 R88 R91

Gene Ontology

Molecular Function

• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5lzx, PDBe:5lzx, PDBj:5lzx
• PDBsum: 5lzx
• PubMed: 27863242
• UniProt: G1SIT5|RL35_RABIT Large ribosomal subunit protein uL29 (Gene Name=RPL35)