Structure of PDB 5lzs Chain h Binding Site BS02

Receptor Information

>5lzs Chain h (length=122) Species: 9986 (Oryctolagus cuniculus)

AKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVR
KSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMRRRLNKHEES
LKTKKQQRKERLYPLRKYAVKA

Ligand information

>5lzs Chain 8 (length=151)

cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
u

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>........>>>..>...>>>....
<<<..>>><<<<<<<<.......>>>>>>>>...................
.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5lzs Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
• Resolution: 3.31 Å
• Binding residue (original residue number in PDB): K5 A6 R10 S42 S45 I47 R48 R51 K52 R56 L58 T59 N62 Q63 K66 L81 R84 P85 K86 T88 R89 R92
• Binding residue (residue number reindexed from 1): K4 A5 R9 S41 S44 I46 R47 R50 K51 R55 L57 T58 N61 Q62 K65 L80 R83 P84 K85 T87 R88 R91

Gene Ontology

Molecular Function

• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5lzs, PDBe:5lzs, PDBj:5lzs
• PDBsum: 5lzs
• PubMed: 27863242
• UniProt: G1SIT5|RL35_RABIT Large ribosomal subunit protein uL29 (Gene Name=RPL35)