Structure of PDB 8ir1 Chain g Binding Site BS02

Receptor Information
>8ir1 Chain g (length=112) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNN
TLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDY
DALDVANKIGII
Ligand information
>8ir1 Chain 8 (length=155) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacugcggccccggguuccucccggggcuacgccugucugagcg
ucgcu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<...>><<<<<<<<<.....>>>>>>>>>...............
.....
Receptor-Ligand Complex Structure
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PDB8ir1 Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		P49 R56 P66 R67 R68 N69 K70 Q108
Binding residue
(residue number reindexed from 1)		P5 R12 P22 R23 R24 N25 K26 Q64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0045296 cadherin binding
GO:1904841 TORC2 complex binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ir1, PDBe:8ir1, PDBj:8ir1
PDBsum8ir1
PubMed37491604
UniProtP62750|RL23A_HUMAN Large ribosomal subunit protein uL23 (Gene Name=RPL23A)

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