Structure of PDB 5k0y Chain g Binding Site BS02

Receptor Information
>5k0y Chain g (length=227) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAVQISKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTRTEIII
LATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIA
QAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSM
KFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPSGKIGP
KKPLPDHVSIVEPKDEILPTTPISEQK
Ligand information
>5k0y Chain F (length=30) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cagacaccauggugcaccugacuccugagg
..............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5k0y eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Resolution5.8 Å
Binding residue
(original residue number in PDB)		T53 R54 Q56 K90 R94 S104 K108 R116 R117 G121 R124 F125 R143 R146 K148
Binding residue
(residue number reindexed from 1)		T53 R54 Q56 K90 R94 S104 K108 R116 R117 G121 R124 F125 R143 R146 K148
Enzymatic activity
Enzyme Commision number 4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0016829 lyase activity
GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Biological Process
GO:0006281 DNA repair
GO:0006412 translation
GO:0006417 regulation of translation
GO:0006915 apoptotic process
GO:0031334 positive regulation of protein-containing complex assembly
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051301 cell division
GO:2001235 positive regulation of apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005819 spindle
GO:0005840 ribosome
GO:0005856 cytoskeleton
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5k0y, PDBe:5k0y, PDBj:5k0y
PDBsum5k0y
PubMed27373335
UniProtG1TNM3|RS3_RABIT Small ribosomal subunit protein uS3 (Gene Name=RPS3)

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