Structure of PDB 5gae Chain g Binding Site BS02

Receptor Information

>5gae Chain g (length=399) Species: 562 (Escherichia coli)

GGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTIIEM
FNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEIKKEGESGR
RKISQYTRYGTLVLAIFQSIGIATGLPNFAFYFTAVVSLVTGTMFLMWLG
EQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAV
LVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVI
PAIFASSIILFPATIASWFGGWNWLTTISLYLQPGQPLYVLLYASAIIFF
CFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGA
LYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSS

Ligand information

>5gae Chain i (length=25) Species: 562 (Escherichia coli)

PPPPPPPPPPPPPPPPPPPPPPPPP

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5gae Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
• Resolution: 3.33 Å
• Binding residue (original residue number in PDB): W173 R181
• Binding residue (residue number reindexed from 1): W148 R156

Gene Ontology

Molecular Function

• GO:0005048 signal sequence binding
• GO:0005515 protein binding
• GO:0008320 protein transmembrane transporter activity

Biological Process

• GO:0006605 protein targeting
• GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
• GO:0006886 intracellular protein transport
• GO:0015031 protein transport
• GO:0032978 protein insertion into membrane from inner side
• GO:0043952 protein transport by the Sec complex
• GO:0065002 intracellular protein transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane
• GO:0031522 cell envelope Sec protein transport complex

External links

• PDB: RCSB:5gae, PDBe:5gae, PDBj:5gae
• PDBsum: 5gae
• PubMed: 26804923
• UniProt: P0AGA2|SECY_ECOLI Protein translocase subunit SecY (Gene Name=secY)