Structure of PDB 3jcs Chain g Binding Site BS02

Receptor Information
>3jcs Chain g (length=125) Species: 5661 (Leishmania donovani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTSRVNRNRKAPRLYMKGTLAGYTRGLHGQTKQTALVRVENVNTREDATW
YVGKRVCYVYHGKKVKRCVRWSKAPARRSTTRALWGRVTRPHGNAGMMRV
KFNGASVPASAIGRRIRVYLYPSQI
Ligand information
>3jcs Chain 2 (length=1119) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccaacugcagaccguacucaucaccgcaucagguccccaagcauagaau
gcucugguacauagagaaagguacacucagggaagucggcaaaauagaug
cguaaguucgcaagaagcauuggcucugagggcaauugccacucagaacu
gcuuacggcggggaauccaacuguauaauuaaaacauagguuugugaugc
auccaagugguguauaucgcaaacugauuucugcccagugcucugaaugu
caacgugacgagauucaccgacgcgcggguaaacggcgggagacucucuu
aagguagccaaaugccucgucuuccaauuagagacgcgcaugaauggauu
aaugagauucccucugucccgaguuacuaucuagcgaaacgacagucaag
ggaacggacuugaagggcuaagcggggaaagaagacccuguugaguuuga
cuccagucuggcucugugcggcgacaucugagguguaguauagguggaag
cgcaagcgcaaaugaaauaccaccacucggaaguugcuucacuuaucgaa
ugaagagaccaauggguuuagcguagucuggcuaugcaccgucuagguuu
gggaguaauuuuauggcggggugugcuugggcgugacucguggguaccca
accgugcuguaaacugaaccaacgggauugccucgugcaguuccgggucu
uguuucgagacaucugccagauggggaguuuggcugcggcuaucuguuac
acgacaacgcagguguccuaaggcgagcucagugggaacaaucucacgua
gaacacaagcguaaaagcuugcuugauuaacgauuuccaguacgaaucga
gacugcgaaagcaaggccagcgauccuuugcgaugaacaaaucauaccag
aggugucagaauaauuaccacagggauaacuggcuuguggcggccaagcg
auagcgacgucgcuuuuugauccuucgaugucggcucuuccuaaccuagc
gccgcagaagacgcuaaggguuggauuguucacccacugacagggaacgu
gagcuggguuuagaccgucgugagacagguugguuuuacccuacuuagcu
ggaaauugcgagaaaaaga
........................<<......>>......<<<<.....>
>>>........<<<<....<<<<.<<<<.<<...............<<<<
<.....<..>......>>>>><<.<<<<<<.<......>..>>>>>>.>>
..........<<<<<<<<<..<<<.........>>>..<<<<<<<....<
<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.....<<
....<<<<......>>>>....>>..>>>>..>>>>>.............
......<...........<<<<<.......>>>>>.....>.....>>..
..>>.>>>>>>>.....>>.>>>>>>>>.>>>>............<<<<<
........>>>>>..<<<<<<<..<<<.<<......<<<<.<<<<<<..<
<<<<.<<<<<<<...<<<.<<<<<<.<<<.....................
............................>>>.>>>>>>.>>>...<<<<<
.....<<<.....<<.....<<<<<<<...>>>>>>>....>>.....<.
..<..................<<<<<<..>>>>>>...............
..>..>................<<<<<<<<.......>>>>>>>>..>>>
...>>>>>.......>>>>>>>..>>>>>..<<<....>>><<<<<<...
........>>>>>>..<<...<<<<<<<...<<<<<<....>>>>>>...
..<<......>>....>>>>>>>...<<..<<<<<<.......>>>>>>.
>>.<<<....>>>.>>........<<<<<<..<<<.......>>>..>>>
>>>.........>>>>..>>>>>>.......<<.<...<.<.<.....<.
...>.....>.>.>....>.>.>.......<<<<<.<<<<<<..<<<<<<
<.<......>.>>>>..>>>.<<<.........>>>.....>>>>>..>.
..>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>>>>>
...................
Receptor-Ligand Complex Structure
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PDB3jcs 2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
H80 R133
Binding residue
(residue number reindexed from 1)
H61 R114
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:3jcs, PDBe:3jcs, PDBj:3jcs
PDBsum3jcs
PubMed27373148
UniProtA0A3Q8II82

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