Structure of PDB 7p7u Chain f Binding Site BS02

Receptor Information
>7p7u Chain f (length=163) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNGHVGFGTGK
AQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGVFGGGRILMKPAVEG
SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEE
VAALRGKSVEEII
Ligand information
Ligand IDSCM
InChIInChI=1S/C14H24N2O7/c1-5-4-6(17)14(20)13(21-5)22-12-10(19)7(15-2)9(18)8(16-3)11(12)23-14/h5,7-13,15-16,18-20H,4H2,1-3H3/t5-,7-,8+,9+,10+,11-,12-,13+,14+/m1/s1
InChIKeyUNFWWIHTNXNPBV-WXKVUWSESA-N
SMILES
SoftwareSMILES
CACTVS 3.341CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O
OpenEye OEToolkits 1.5.0CC1CC(=O)C2(C(O1)OC3C(C(C(C(C3O2)NC)O)NC)O)O
OpenEye OEToolkits 1.5.0C[C@@H]1CC(=O)[C@]2([C@@H](O1)O[C@@H]3[C@H]([C@@H]([C@@H]([C@@H]([C@H]3O2)NC)O)NC)O)O
CACTVS 3.341CN[CH]1[CH](O)[CH](NC)[CH]2O[C]3(O)[CH](O[CH](C)CC3=O)O[CH]2[CH]1O
ACDLabs 10.04O=C1C2(OC3C(NC)C(O)C(NC)C(O)C3OC2OC(C1)C)O
FormulaC14 H24 N2 O7
NameSPECTINOMYCIN;
ACTINOSPECTACIN;
ESPECTINOMICINA;
CHX-3101
ChEMBLCHEMBL1167
DrugBankDB00919
ZINCZINC000053006806
PDB chain7p7u Chain a Residue 1660 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7p7u Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K26 G27
Binding residue
(residue number reindexed from 1)		K24 G25
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7p7u, PDBe:7p7u, PDBj:7p7u
PDBsum7p7u
PubMed35387982
UniProtA0A1B4XKW0

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