Structure of PDB 6zol Chain f Binding Site BS02

Receptor Information
>6zol Chain f (length=72) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKRKKKSCTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECG
AGVFMASHFDRHYCGKCCLTYC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6zol Chain f Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6zol SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		C121 C126 C141 C144
Binding residue
(residue number reindexed from 1)		C44 C49 C64 C67
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zol, PDBe:6zol, PDBj:6zol
PDBsum6zol
PubMed32908316
UniProtP62979|RS27A_HUMAN Ubiquitin-ribosomal protein eS31 fusion protein (Gene Name=RPS27A)

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