Structure of PDB 7osa Chain eL43 Binding Site BS02

Receptor Information
>7osa Chain eL43 (length=91) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKRTKKVGITGKYGVRYGSSLRRQVKKLEIQQHARYDCSFCGKKTVKRGA
AGIWTCSCCKKTVAGGAYTVSTAAAATVRSTIRRLREMVEA
Ligand information
>7osa Chain 18S (length=1717) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauacagugaaacugcgaauggcucauuaa
aucaguuaucguuuauuugauaguucccuacaugguauaacugugguaau
ucuagagcuaauacaugcuuaaaaucucagagauguauuuauuagauaaa
aagaugauucauaauaacuuuucgaaucgcauggccuugugcuggcgaug
guucauucaaauuucugcccuaucaacuuucgaugguaggauaguggccu
accaugguuucaacggguaacggggaauaaggguucgauuccggagaggg
agccugagaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauu
acccaauccuaauucagggagguagugacaauaaauaacgauacagggcc
cauucgggucuuguaauuggaaugaguacaauguaaauaccuuaacgagg
aacaauuggagggcaagucuggugccagcagccgcgguaauuccagcucc
aauagcguauauuaaaguuguugcaguuaaaaagcucguaguugaacuuu
gggcccgguuggccggucggauuuccaacggggccuuuccuucuggcuaa
ccuggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaagcag
gcguauugcucgaauauauuagcauggaauaauagaauaggacguuuggu
ucuauuuuucuaggaccaucguaaugauuaauagggacggucgggggcau
caguauucaauugucagaggugaaauucuuggauuuauugaagacuaacu
acugcgaaagcauuugccaaggacguuuucauuaaucaagaacgaaaguu
aggggaucgaagaugaucagauaccgucguagucuuaaccauaaacuaug
ccgacuagggaucgggugguguuuuuuuaaugacccacucggcaccuuac
gagaaaucaaagucuuuggguucuggggggaguauggucgcaaggcugaa
acuuaaaggaauugacggaagggcaccaccaggaguggagccugcggcuu
aauuugacucaacacggggaaacucaccagguccagacacaauaaggauu
gacagauugagagcucuuucuugauuuugugggugguggugcauggccgu
ucuuaguugguggagugauuugucugcuuaauugcgauaacgaacgagac
cuuaaccuacuaaauaguggugcuagcauuugcugguuauccacuucuua
gagggacuaucgguuucaagccgauggaaguuugaggcaauaacaggucu
gugaugcccuuagacguucugggccgcacgcgcgcuacacugacggagcc
agcgagucuaaccuuggccgagaggucuugguaaucuugugaaacuccgu
cgugcuggggauagagcauuguaauuauugcucuucaacgaggaauuccu
aguaagcgcaagucaucagcuugcguugauuacgucccugcccuuuguac
acaccgcccgucgcuaguaccgauugaauggcuuagugaggccucaggau
cugcuuagagaagggggcaacuccaucucagagcggagaauuuggacaaa
cuuggucauuuagaggaacuaaaagucguaacaagguuuccguaggugaa
ccugcggaaggaucauu
...<<<<<.[.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<......>>...>>.>>......<<......
..<<<..<<..<<....<<<............<<......<<.<<<....
.>>>.>>......>>........<<<<...>>>>....<<<<<<.....[
...........>>>>>>.........<<<<..<<<.....>>>.>>>>..
..>>>...>>>>..>>>.<<<....<<<....<<<<<<<<.......>>>
>>>>>>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.
<<<..........>>>.>>.<.<<....>>.>...>>>>>>.........
<<<....<<<.....>>>..>>>..>....>.>.....<<<<<<<<....
..........>>>>>.>>>......<<..<...........>..>>....
.....<<<<<((....<.<<<<.....<<..))>>.......>>>>>>>>
>>..>>>>>>>>>>.........<<<((.....<.<<...<<<.<<....
<<<<.<.<<..................>>..>>>>>....<<<..<....
.........>..>>>...<<<<<.<<.......<<...<.......>..<
<<.....>>>....>>......>>.>>..>>>.........<<...<.<<
<<<<....].>>>>>>.>..>>.....>>....<<<<<<.<<...<<<<.
.<<..<<<<<<.<...<<<......>>>......>.>>>>>>..>>....
..<<<....>>>..>>>>...>>>>>.>>>...>>>...>>.>....<<<
<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<.<<.<<<..<<<<<<<<.<<<........>>>>>>>>>>>..>>>...
<<..))>>...>>.....>>>.>>>.<<<......<<<<....>>>>...
.>>>..)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<.<..
....<<........>>..........<<<<<.<....<<<<<........
<<.<<<........>>>.>>......>>>>>...<<.<<<..<<.<<<<<
<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<
<<<<.<<..<<<<..<<<<<.<<<<<<....>>>>>>...>>>>>..>>>
>.>>....<<<<<<.....>>>>>>.......>>>>>....>>>.>>>..
...>>>>>>>.....>.>>>>>...>..>>>>.>>>.....<<<<<<<..
....<<.....<<..<<<<....>>>>..>>....>>.......>>>>>>
>...........<<<<<<..........>>>>>>..........>>>>>>
....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>
>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<.<<......<
<<<<<<.<<...<........>.....>>.>>>>>>>......>>.>..>
>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<....
>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7osa Accuracy mechanism of eukaryotic ribosome translocation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R24 R84
Binding residue
(residue number reindexed from 1)		R23 R83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0046872 metal ion binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0044391 ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7osa, PDBe:7osa, PDBj:7osa
PDBsum7osa
PubMed34853469
UniProtP0CX25|RL43A_YEAST Large ribosomal subunit protein eL43A (Gene Name=RPL43A)

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