Structure of PDB 7osa Chain eL19 Binding Site BS02

Receptor Information
>7osa Chain eL19 (length=174) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANLRTQKRLAASVVGVGKRKVWLDPNETSEIAQANSRNAIRKLVKNGTIV
KKAVTVHSKSRTRAHAQSKREGRHSGYGKRKGTREARLPSQVVWIRRLRV
LRRLLAKYRDAGKIDKHLYHVLYKESKGNAFKHKRALVEHIIQAKADAQR
EKALNEEAEARRLKNRAARDRRAQ
Ligand information
>7osa Chain 18S (length=1717) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauacagugaaacugcgaauggcucauuaa
aucaguuaucguuuauuugauaguucccuacaugguauaacugugguaau
ucuagagcuaauacaugcuuaaaaucucagagauguauuuauuagauaaa
aagaugauucauaauaacuuuucgaaucgcauggccuugugcuggcgaug
guucauucaaauuucugcccuaucaacuuucgaugguaggauaguggccu
accaugguuucaacggguaacggggaauaaggguucgauuccggagaggg
agccugagaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauu
acccaauccuaauucagggagguagugacaauaaauaacgauacagggcc
cauucgggucuuguaauuggaaugaguacaauguaaauaccuuaacgagg
aacaauuggagggcaagucuggugccagcagccgcgguaauuccagcucc
aauagcguauauuaaaguuguugcaguuaaaaagcucguaguugaacuuu
gggcccgguuggccggucggauuuccaacggggccuuuccuucuggcuaa
ccuggcgaaccaggacuuuuacuuugaaaaaauuagaguguucaaagcag
gcguauugcucgaauauauuagcauggaauaauagaauaggacguuuggu
ucuauuuuucuaggaccaucguaaugauuaauagggacggucgggggcau
caguauucaauugucagaggugaaauucuuggauuuauugaagacuaacu
acugcgaaagcauuugccaaggacguuuucauuaaucaagaacgaaaguu
aggggaucgaagaugaucagauaccgucguagucuuaaccauaaacuaug
ccgacuagggaucgggugguguuuuuuuaaugacccacucggcaccuuac
gagaaaucaaagucuuuggguucuggggggaguauggucgcaaggcugaa
acuuaaaggaauugacggaagggcaccaccaggaguggagccugcggcuu
aauuugacucaacacggggaaacucaccagguccagacacaauaaggauu
gacagauugagagcucuuucuugauuuugugggugguggugcauggccgu
ucuuaguugguggagugauuugucugcuuaauugcgauaacgaacgagac
cuuaaccuacuaaauaguggugcuagcauuugcugguuauccacuucuua
gagggacuaucgguuucaagccgauggaaguuugaggcaauaacaggucu
gugaugcccuuagacguucugggccgcacgcgcgcuacacugacggagcc
agcgagucuaaccuuggccgagaggucuugguaaucuugugaaacuccgu
cgugcuggggauagagcauuguaauuauugcucuucaacgaggaauuccu
aguaagcgcaagucaucagcuugcguugauuacgucccugcccuuuguac
acaccgcccgucgcuaguaccgauugaauggcuuagugaggccucaggau
cugcuuagagaagggggcaacuccaucucagagcggagaauuuggacaaa
cuuggucauuuagaggaacuaaaagucguaacaagguuuccguaggugaa
ccugcggaaggaucauu
...<<<<<.[.((((>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<......>>...>>.>>......<<......
..<<<..<<..<<....<<<............<<......<<.<<<....
.>>>.>>......>>........<<<<...>>>>....<<<<<<.....[
...........>>>>>>.........<<<<..<<<.....>>>.>>>>..
..>>>...>>>>..>>>.<<<....<<<....<<<<<<<<.......>>>
>>>>>>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.
<<<..........>>>.>>.<.<<....>>.>...>>>>>>.........
<<<....<<<.....>>>..>>>..>....>.>.....<<<<<<<<....
..........>>>>>.>>>......<<..<...........>..>>....
.....<<<<<((....<.<<<<.....<<..))>>.......>>>>>>>>
>>..>>>>>>>>>>.........<<<((.....<.<<...<<<.<<....
<<<<.<.<<..................>>..>>>>>....<<<..<....
.........>..>>>...<<<<<.<<.......<<...<.......>..<
<<.....>>>....>>......>>.>>..>>>.........<<...<.<<
<<<<....].>>>>>>.>..>>.....>>....<<<<<<.<<...<<<<.
.<<..<<<<<<.<...<<<......>>>......>.>>>>>>..>>....
..<<<....>>>..>>>>...>>>>>.>>>...>>>...>>.>....<<<
<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<.<<.<<<..<<<<<<<<.<<<........>>>>>>>>>>>..>>>...
<<..))>>...>>.....>>>.>>>.<<<......<<<<....>>>>...
.>>>..)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<.<..
....<<........>>..........<<<<<.<....<<<<<........
<<.<<<........>>>.>>......>>>>>...<<.<<<..<<.<<<<<
<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<
<<<<.<<..<<<<..<<<<<.<<<<<<....>>>>>>...>>>>>..>>>
>.>>....<<<<<<.....>>>>>>.......>>>>>....>>>.>>>..
...>>>>>>>.....>.>>>>>...>..>>>>.>>>.....<<<<<<<..
....<<.....<<..<<<<....>>>>..>>....>>.......>>>>>>
>...........<<<<<<..........>>>>>>..........>>>>>>
....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>
>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<.<<......<
<<<<<<.<<...<........>.....>>.>>>>>>>......>>.>..>
>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<....
>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7osa Accuracy mechanism of eukaryotic ribosome translocation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
A159 N166 R170 R173
Binding residue
(residue number reindexed from 1)
A158 N165 R169 R172
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7osa, PDBe:7osa, PDBj:7osa
PDBsum7osa
PubMed34853469
UniProtP0CX82|RL19A_YEAST Large ribosomal subunit protein eL19A (Gene Name=RPL19A)

[Back to BioLiP]