Structure of PDB 5i4l Chain e1 Binding Site BS02

Receptor Information
>5i4l Chain e1 (length=76) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKKRKKKVYTTPKKIKHKHKKVKLAVLSYYKVDAEGKVTKLRRECSNPTC
GAGVFLANHKDRLYCGKCHSVYKVNA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5i4l Chain e1 Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5i4l Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		C141 C144
Binding residue
(residue number reindexed from 1)		C65 C68
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:5i4l, PDBe:5i4l, PDBj:5i4l
PDBsum5i4l
PubMed27296282
UniProtP05759|RS31_YEAST Ubiquitin-ribosomal protein eS31 fusion protein (Gene Name=RPS31)

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