Structure of PDB 8ow0 Chain e Binding Site BS02

Receptor Information
>8ow0 Chain e (length=97) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPSELALYEIRKYQRSTDLLISKIPFARLVKEVTDEFTTKDQDLRWQSMA
IMALQEASEAYLVGLLEHTNLLALHAKRITIMKKDMQLARRIRGQFI
Ligand information
>8ow0 Chain E (length=120) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tttaactttcggaaatcaaatacactaatattaaaacgcgggggacagcg
cgtacgtgcgtttaagcggtgctagagctgtctacgaccaattgagcggc
ctcggcaccatgtgacttat
Receptor-Ligand Complex Structure
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PDB8ow0 Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		K163 R177 W178 Q179 K209 R210 I211
Binding residue
(residue number reindexed from 1)		K31 R45 W46 Q47 K77 R78 I79
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0019237 centromeric DNA binding
GO:0030527 structural constituent of chromatin
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0000278 mitotic cell cycle
GO:0009303 rRNA transcription
GO:0030543 2-micrometer plasmid partitioning
GO:0051382 kinetochore assembly
GO:0061644 protein localization to CENP-A containing chromatin
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000779 condensed chromosome, centromeric region
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005729 2-micrometer circle DNA
GO:0005777 peroxisome
GO:0032991 protein-containing complex
GO:0043505 CENP-A containing nucleosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ow0, PDBe:8ow0, PDBj:8ow0
PDBsum8ow0
PubMed37506202
UniProtP36012|CENPA_YEAST Histone H3-like centromeric protein CSE4 (Gene Name=CSE4)

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