Structure of PDB 7ls1 Chain d2 Binding Site BS02

Receptor Information
>7ls1 Chain d2 (length=86) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK
Ligand information
>7ls1 Chain C2 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<<<<
....>>>>.....<.<<<......>>.............>>>..>...>>
>....<<....>><<<<<<<<<.....>>>>>>>>>..............
......
Receptor-Ligand Complex Structure
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PDB7ls1 Functionally distinct roles for eEF2K in the control of ribosome availability and p-body abundance.
Resolution3.3 Å
Binding residue
(original residue number in PDB)
R20 R21 C22 G23 Y39 T59 G60 G62 R63 M64 H66 L67 K68 Y71 R72 R73 F74 H76 R79 E80 G81 T82 P84 K85 P86 K87
Binding residue
(residue number reindexed from 1)
R19 R20 C21 G22 Y38 T58 G59 G61 R62 M63 H65 L66 K67 Y70 R71 R72 F73 H75 R78 E79 G80 T81 P83 K84 P85 K86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0140236 translation at presynapse
GO:0140242 translation at postsynapse
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0045202 synapse
GO:0098793 presynapse
GO:0098794 postsynapse
GO:1990904 ribonucleoprotein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:7ls1, PDBe:7ls1, PDBj:7ls1
PDBsum7ls1
PubMed34815424
UniProtQ9D823|RL37_MOUSE Large ribosomal subunit protein eL37 (Gene Name=Rpl37)

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