Structure of PDB 6zmw Chain d Binding Site BS02

Receptor Information

>6zmw Chain d (length=142) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDENW
FYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVARR
VLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKK

Ligand information

InChI=1S/Mg/q+2

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Mg

Name

MAGNESIUM ION

PDB chain

6zmw Chain d Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	6zmw Structure of a human 48Stranslational initiation complex.
Resolution	3.7 Å
Binding residue (original residue number in PDB)	G80 G81
Binding residue (residue number reindexed from 1)	G78 G79
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0005515	protein binding
GO:0017134	fibroblast growth factor binding
GO:0019901	protein kinase binding
GO:0042802	identical protein binding

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181	cytoplasmic translation
GO:0002548	monocyte chemotaxis
GO:0006364	rRNA processing
GO:0006412	translation
GO:0007000	nucleolus organization
GO:0030218	erythrocyte differentiation
GO:0030490	maturation of SSU-rRNA
GO:0031640	killing of cells of another organism
GO:0042274	ribosomal small subunit biogenesis
GO:0050829	defense response to Gram-negative bacterium
GO:0060265	positive regulation of respiratory burst involved in inflammatory response
GO:0060266	negative regulation of respiratory burst involved in inflammatory response
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005925	focal adhesion
GO:0014069	postsynaptic density
GO:0016020	membrane
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0032040	small-subunit processome
GO:0070062	extracellular exosome
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6zmw, PDBe:6zmw, PDBj:6zmw
PDBsum	6zmw
PubMed	32883864
UniProt	P39019\|RS19_HUMAN Small ribosomal subunit protein eS19 (Gene Name=RPS19)

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