Structure of PDB 7w5z Chain c2 Binding Site BS02

Receptor Information
>7w5z Chain c2 (length=576) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MWGNLWTEASYQLNFNIGFSSLRSDVLIHLAQWQYWWWFWFALIWSFYYF
IILKVARFRVLKMRPKISTSYRPHGKWGDFLACIIPLIWCINILTNSNLI
LRLIEWQNESSLFTVRVRARQWYWIYKFELKNFTDILSTPKNIGNNRWQI
NTFGELQTADDYLHVLQLRSQNKWVKNYWNRSLQETGKTNKAHVISPQEQ
LRLSLINQYKSLNLSSSIKHNAPFINRDLYVFDDLFSYNLGDITTKKSLF
NDKNSFLTSYSYLNNNSWNNNEFDLIDNLPFTTLFDNNDLFNNYKSFFQD
SIFNSPKKQLSSDSKQLFKHIIYRSIKNNIIQDYTKLVKHEDFDEYSRWI
KRSPGEVLPLRIIKYPLGLETIHNNIFENTNNEGNVELFRLRFNSNSSKM
QHKLVQDTIYLTLKQKRYNRKKVVAPQIKYYTDLVKYTGKPYLSNDKLLK
QSIYDQTTQYKLIKKNKKRGELIPVTLARRILRTKKTLVLPAHVNITLIT
NSYDIVHSWFIPGLGIKLDCVPGRSTHHTFFIDNVGFYYGQCAEICGRYH
HHMPIRVCALPFEHFLLWWNTFGLPK
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain7w5z Chain c2 Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7w5z Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Resolution3.02 Å
Binding residue
(original residue number in PDB)		C549 E551 C553 H557
Binding residue
(residue number reindexed from 1)		C542 E544 C546 H550
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0042773 ATP synthesis coupled electron transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7w5z, PDBe:7w5z, PDBj:7w5z
PDBsum7w5z
PubMed35357889
UniProtQ950Y9

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