Structure of PDB 8gym Chain c1 Binding Site BS02

Receptor Information
>8gym Chain c1 (length=674) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSVNNYFYYLDRIKKLFTYLNDLRKHILKKYVYTINHKRIAINYLYFSMV
TGLSGAALATMIRLELAHPGSPFFKGDSLRYLQVVTAHGLIMVFFVVVPI
LFGGFANFLIPYHVGSKDVAYPRLNSIGFWIQPCGYILLAKIGFLRPQFW
RYYDKTSFSFPFLEKMKYNQYKEYKNDYLFYLDFLKKEITDDHSFFWKAR
KVIKLPQYSVFSFVPLKLMMWKTMINYPESFWYAASRVVQSRRKKVFVTK
CSARTLTTAGWTFITPFSSNIKYTGVGSQDILILSVVFAGISTTISFTNL
LITRRTLAMPGLRHRRVLMPFVTISIFLTLRMLATITPVLGAAVIMMAFD
RHWQTTFFEYAYGGDPILSQHLFWFFGHPEVYVLIIPTFGFINMIVPHNN
TRRVASKHHMIWAIYVMAYMGYLVWGHHMYLVGLDHRSRTMYSTITIMIS
MPATIKVVNWTLSLVNGALKIDLPFLFSMSFLLLFLVAGFTGMWLSHVSL
NVSMHDTFYVVAHFHIMLSGAAMTGIFSGIYYYFNALFGVKYSRMFGYMH
LIYYSGGQWVAFVPLFYLGFSGMPRRIHDYPVVFMGWHSMSTTGHFITLV
GIIFFFLMMFDSHIERRASTSTTLGLPRWYKRISYYIFKIRYLQHTKSKM
NGIPGSTVRLMLINRHFVEYEVYE
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain8gym Chain c1 Residue 705 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8gym Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae.
Resolution2.96 Å
Binding residue
(original residue number in PDB)		H391 H440 H441
Binding residue
(residue number reindexed from 1)		H378 H427 H428
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006119 oxidative phosphorylation
GO:0006123 mitochondrial electron transport, cytochrome c to oxygen
GO:0009060 aerobic respiration
GO:0015990 electron transport coupled proton transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8gym, PDBe:8gym, PDBj:8gym
PDBsum8gym
PubMed37248254
UniProtQ950Y4

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