Structure of PDB 6x0n Chain c Binding Site BS02

Receptor Information
>6x0n Chain c (length=102) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILEL
AGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQSVL
LP
Ligand information
>6x0n Chain j (length=160) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ctatgatgccctggagaatcccggtgccgaggccgctcaattggtcgtag
acagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgtttta
accgccaaggggattactccctagtctccaggcacgtgtcagatatatac
atcctgtgca
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6x0n Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Resolution10.0 Å
Binding residue
(original residue number in PDB)		R29 R42 K75 T76 R77
Binding residue
(residue number reindexed from 1)		R14 R27 K60 T61 R62
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6x0n, PDBe:6x0n, PDBj:6x0n
PDBsum6x0n
PubMed32939087
UniProtP06897|H2A1_XENLA Histone H2A type 1

[Back to BioLiP]