Structure of PDB 5a2q Chain c Binding Site BS02

Receptor Information

>5a2q Chain c (length=61) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLT
LLESEREARRL

Ligand information

>5a2q Chain 3 (length=257) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cuccccugugaggaacuacugucuucacgcagaaagcgucuagccauggc
guuaguaugagugucgugcagccuccaggacccccccucccgggagagcc
auaguggucugcggaaccggugaguacaccggaauugcgagauuugggcg
ugcccccgcaagacugcuagccgaguaguguugggucgcgaaaggccuug
ugguacugccugauagggugcuugcgagugccccgggaggucucguagac
caccaug

....<<<<.<<<<.....<<<<<..<<<.<<....<<<<<.......>>>
>>.....>>.>>>..>.>>>>>>>>>>>>......<<<<<<<<<<<.<<<
<<<<<<<<<<<<<<..<<<<<<....>>>>>><<<<....>>>>.<<<<.
.>>>>>>>>.>>>>>>>>><<<.....<<........>>....>>>....
>>>>.>><<<<....>>>><<..(((((.>>>>>>>>>>>.)))))....
.......

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5a2q Cryo-Em Structure of Hepatitis C Virus Ires Bound to the Human Ribosome at 3.9 Angstrom Resolution
Resolution	3.9 Å
Binding residue (original residue number in PDB)	K16 Q29 R31 D37 S39 S41 I43 R67
Binding residue (residue number reindexed from 1)	K9 Q22 R24 D30 S32 S34 I36 R60

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome

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Cellular Component

External links

PDB	RCSB:5a2q, PDBe:5a2q, PDBj:5a2q
PDBsum	5a2q
PubMed	26155016
UniProt	P62857\|RS28_HUMAN Small ribosomal subunit protein eS28 (Gene Name=RPS28)

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