Structure of PDB 3jcs Chain c Binding Site BS02

Receptor Information
>3jcs Chain c (length=222) Species: 5661 (Leishmania donovani) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QQTENFKKAVVARKAAKAALKKTAYLRARKYSREYRGAEKKLVTLRRQAA
SHGNYYLEAKPKVAVVTRIRGIAKVNPKQRKILQLLRLRQIFNTVFVKMN
KPMENMLRAVEPYIAYGYPSLATVRAMVYKRGYLKINGQRVKITDNQMIK
DKYNNADIVCAEDMVNQIYTCGKHFRTVTHGMWPFKLAPPAGGMRQKRRH
FVEGGDYGNRDTLINRFLARMI
Ligand information
>3jcs Chain 8 (length=119) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucgaguacgaccauacuugagugaaaacaccauaucccguccgauuugug
aaguuaagcacucaaggcucaguuaguacugaggucagugaugacucggg
aacccugagugccguacuc
...<<<<<<......<<<<<<<......<<<<<..............>>>
..>>.....>>>>>>><<<<<<......<<<<<..<<....>>.>>>>>.
....>>>>>>..>>>>>>.
Receptor-Ligand Complex Structure
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PDB3jcs 2.8- angstrom Cryo-EM Structure of the Large Ribosomal Subunit from the Eukaryotic Parasite Leishmania.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		P142 R228 R229 H230 V232 E233
Binding residue
(residue number reindexed from 1)		P112 R198 R199 H200 V202 E203
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3jcs, PDBe:3jcs, PDBj:3jcs
PDBsum3jcs
PubMed27373148
UniProtE9BI29

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