Structure of PDB 6ot3 Chain b Binding Site BS02

Receptor Information

>6ot3 Chain b (length=56) Species: 562 (Escherichia coli)

AVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRG
RKVIAK

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 6ot3 Chain 1 Residue 3001

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6ot3 The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
• Resolution: 3.9 Å
• Binding residue (original residue number in PDB): R16 R17
• Binding residue (residue number reindexed from 1): R15 R16
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding

Biological Process

• GO:0000027 ribosomal large subunit assembly
• GO:0000302 response to reactive oxygen species
• GO:0002181 cytoplasmic translation
• GO:0006412 translation
• GO:0009314 response to radiation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6ot3, PDBe:6ot3, PDBj:6ot3
• PDBsum: 6ot3
• PubMed: 31189921
• UniProt: P0A7N4|RL32_ECOLI Large ribosomal subunit protein bL32 (Gene Name=rpmF)