Structure of PDB 5t5h Chain b Binding Site BS02

Receptor Information
>5t5h Chain b (length=144) Species: 5693 (Trypanosoma cruzi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTRFKKTRHQRGSTFCGYGRVGKHRKHPSGRGNAGGQHHHRINFDKYHPG
YFGKCGMNHYHLKKNPLWKPTINLNNLAKLIAKDEALKAKKGETLPVVDL
LANGYSKLLGNGHLQTPCIVKARWVSKLADKKIRKAGGAVVLQA
Ligand information
>5t5h Chain B (length=941) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acugcagaccguacucaucaccgcaucagguccccaagcauacaaugcuc
ugguacauagagaaagguacacucagggaagucggcaaaauagaugcgua
aguucgcaagaagcauuggcucugagggcaacaacucagaacugcuuacg
gcggggaauccaacuguauaauuaaaacauagguuugugaugcauccaag
ugguguaugucgcaaacugauuucugcccagugcucugugaagagguuca
ccggcgcggguaaacggcaagguagccaaaugccucgucuuccaauuaga
gacgcgcaugaauggauuaaugagauucccucugucccgaguuacuaucu
agcgaaacgacagucaagggaacggacuugaagggcuaagcggggaaaga
agacccuguugaguuugacuccagucuggcucugugaggcgagcuucacu
uaucgaaugaagagaccaauggguuucgcguagucugcgggcuaugcacc
gucucugaaccaacggagucuuguuucgagacaucugccagauggggagu
uuggcuggggcggcauaucuguuacacgacaacgcagguguccuaaggcg
agcucagugggaucucacguagaacacaagcguaaaagcuugcuugauua
acgauuuccaguacgaaucgagacugcgaaagcaaggccagcgauccuuu
gcguaugaacaaaucauaccagaggugucagaauaauuaccacagggaua
acuggcuuauccuucgaugucggcucuuccuaaccuagcggcuaaggguu
ggauuguucacccacugacagggaacgugagcuggguuuagaccgucgug
agacagguugguuuuacccuacuuagcuggaaauugcgagaaaaaaaaaa
uuuuuuaaaauuuuuuuuuuuuuuacuugguacgaaaaaaa
....................<<......>>......<<<<.....>>>>.
.......<<<<....<<<<.<<<<.<<...............<<<<<...
............>>>>><<.<<<<<<........>>>>>>.>>.......
...<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<....
.>>>>......>>>>>>>...<<...<<..<<<<<<.<<<<<....>>>>
>......>>>>..>>>>.......<...........<<<<<.......>>
>>>.....>.....>>....>>.>>>>>>>.....>>.>>>>>>>>.>>>
>............<<<<<........>>>>>..<<<<<<<..<<<.<<..
....<<<<.<.<<<<..<<<<<.<<<<<<<...<<<<<<<..>>>>>>>.
..<<<<<.....<<<<....<<.....<<<<<<<......>>>>>>>.>>
.................>>>>...>>>>>.......>>>>>>>..>>>>>
...<<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<
<<<...<<<<<..>>>>>.....<<......>>....>>>>>>>...<<.
..<<<<<.......>>>>>..>>.<<<....>>>.>>........<<<<<
<.<<<<<.......>>>>>>>>>>>.........>>>>...>>>>>....
...<<....>.>.......<<<<<.<<<<<<..<<<<<<.>>>>..>>.<
<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<...
.>>>.>>>>....>>..>>>.>>>>>>>..................<<<.
.>>>..<<...>>.<<<<<<...<.......>...>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5t5h Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		R42 I43 G54 K55 C56 G57 M58 N59 H60 K64
Binding residue
(residue number reindexed from 1)		R41 I42 G53 K54 C55 G56 M57 N58 H59 K63
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0043232 intracellular non-membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5t5h, PDBe:5t5h, PDBj:5t5h
PDBsum5t5h
PubMed27791004
UniProtQ4E4Q8

[Back to BioLiP]