Structure of PDB 8fvy Chain a Binding Site BS02

Receptor Information
>8fvy Chain a (length=96) Species: 941442 (Giardia intestinalis assemblage A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVKRRNNGRSKYNCGHTNIVRCQNCHRCVPKDKVIKRFTIRNIVDNTIAD
DVLNACVIQGFAIPKLYNKVQYCVSCSIHNHIVRVRSREDRKIRTP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8fvy Chain a Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8fvy The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function
Resolution2.94 Å
Binding residue
(original residue number in PDB)
Q33 N34 Y82
Binding residue
(residue number reindexed from 1)
Q23 N24 Y72
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8fvy, PDBe:8fvy, PDBj:8fvy
PDBsum8fvy
PubMed38242118
UniProtA8BQZ7

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