Structure of PDB 6x0n Chain a Binding Site BS02

Receptor Information
>6x0n Chain a (length=96) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>6x0n Chain j (length=160) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ctatgatgccctggagaatcccggtgccgaggccgctcaattggtcgtag
acagctctagcaccgcttaaacgcacgtacgcgctgtcccccgcgtttta
accgccaaggggattactccctagtctccaggcacgtgtcagatatatac
atcctgtgca
Receptor-Ligand Complex Structure
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PDB6x0n Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Resolution10.0 Å
Binding residue
(original residue number in PDB)		H39 R40 Y41 R42 P43 G44 T45 V46 A47 R49 R63 K64 L65 P66 R69 R83
Binding residue
(residue number reindexed from 1)		H2 R3 Y4 R5 P6 G7 T8 V9 A10 R12 R26 K27 L28 P29 R32 R46
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6x0n, PDBe:6x0n, PDBj:6x0n
PDBsum6x0n
PubMed32939087
UniProtP84233|H32_XENLA Histone H3.2

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