Structure of PDB 6ks6 Chain a Binding Site BS02

Receptor Information
>6ks6 Chain a (length=546) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QLFNNSRSDTLFLGGEKISGDDIRNQNVLATMAVANVVKSSLGPVGLDKM
LVDDIGDFTVTNDGATILSLLDVQHPAGKILVELAQQQDREIGDGTTSVV
IIASELLKRANELVKNKIHPTTIITGFRVALREAIRFINEVLSTSVDTLG
KETLINIAKTSMSSKIIGADSDFFSNMVVDALLAVKTQNSKGEIKYPVKA
VNVLKAHGKSATESLLVPGYALNCTVASQAMPKRIAGGNVKIACLDLNLQ
KARMAMGVQINIDDPEQLEQIRKREAGIVLERVKKIIDAGAQVVLTTKGI
DDLCLKEFVEAKIMGVRRCKKEDLRRIARATGATLVSSMSNLEGEETFES
SYLGLCDEVVQAKFSDDECILIKGTSKHSSSSIILRGANDYSLDEMERSL
HDSLSVVKRTLESGNVVPGGGCVEAALNIYLDNFATTVGSREQLAIAEFA
AALLIIPKTLAVNAAKDSSELVAKLRSYHAASQMAKPEKRRSYRNYGLDL
IRGKIVDEIHAGVLEPTISKVKSLKSALEACVAILRIDTMITVDPE
Ligand information
Ligand IDAF3
InChIInChI=1S/Al.3FH/h;3*1H/q+3;;;/p-3
InChIKeyKLZUFWVZNOTSEM-UHFFFAOYSA-K
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		F[Al](F)F
FormulaAl F3
NameALUMINUM FLUORIDE
ChEMBL
DrugBank
ZINC
PDB chain6ks6 Chain a Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ks6 An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity.
Resolution2.99 Å
Binding residue
(original residue number in PDB)		D65 D96 T98 T99 K167 D404
Binding residue
(residue number reindexed from 1)		D63 D94 T96 T97 K165 D402
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D65 T98 T99 D404
Catalytic site (residue number reindexed from 1) D63 T96 T97 D402
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0051086 chaperone mediated protein folding independent of cofactor
Cellular Component
GO:0005737 cytoplasm
GO:0005832 chaperonin-containing T-complex
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ks6, PDBe:6ks6, PDBj:6ks6
PDBsum6ks6
PubMed31492816
UniProtP12612|TCPA_YEAST T-complex protein 1 subunit alpha (Gene Name=TCP1)

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