Structure of PDB 8urw Chain Z Binding Site BS02

Receptor Information
>8urw Chain Z (length=1235) Species: 32046 (Synechococcus elongatus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EAKSAPIFRNRVIDKKQLKKLIGWTFAHYGTAKTAVVADDLKALGFRYAT
RAGVSISIDDLKVPGSKAELLESAEKRIQETEDRYTRGEITEVERFQKVI
DTWANTNDELTDRVVKNFRESDPLNSVYMMAFSGARGNISQVRQLVGMRG
LMANPQGEIIDLPIKTNFREGLTVTEYIISSYGARKGLVDTALRTADSGY
LTRRLVDVSQDVIIHEVDCGTSRGLFVEAMTDGDRILIPISQRLLGRVTA
EAVLDPSTDEVLAEAGQDINEDLANRIEKAGIKKVKVRSPLTCEAARSVC
QKCYGWSLAHAQMVDMGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGET
ARLLRAPVAGTIKLGKKARTRPYRTRHGEEALLAEANFDLVLEGKGRKET
FAILQGSTIFVQDGDKVAAEAILAEVPVSGRTKRTVEKATKDVATDLAGE
IRFQDIVPEEKTDRQGNTTRIAQRGGLLWVLAGDVYNLLPGAEPTVKNGD
RVEVGDVLAETKLTTERGGTVRMGEDNGSSTHREVEIITASVVLDTATVK
AEASQGREHYVIETKGGQRFNLLAAPGTKVTTGHVVAELIDSRYRTQTGG
LLKYSGVEISKKGRAKAKQGYEVTKGGTLLWIPEETHEVNKDISLLNVED
GQLVEAGTEVVKDIFCQTTGIVSVTQNNDILREIVIKPGDVHVLDDPDTA
AKYDEGRLVNAGEEVFPGLTAEQLVWAEAVDGTDGPLLLLRPVQELVIPD
EPPVPSQDSSQESSSRSIRLRAVQRLQFQDGERIKSVEGVDLLRTQLVLE
SEEGSSQLSADIELLPDSKDPETLRLQLVIIEPVVIRRDVASDTTHGSTH
TELRVKDGQKVKPGAVIACTQIQCKEAGVVRGIQEGSEAVRRLLVERERD
CVTLDLDVTAATQLQPGSLIVAGTQLVDGIIAPESGEVRAIAPGQLQLRI
ARPYRVSQGAVLHVEDKGLVQRGDNLVLLVFERAKTGDIIQGLPRIEELL
EARKPKEACILARRPGVAHINYSDDDAIDIQVIEADGTQADYPVGPGQPL
IISDGETVDAGQALTDGPANPHDLLEIYYDYFREQLGEDYEAALESLRRV
QALLVNEVQSVYQSQGIDISDKHIEVIVRQMTSKVRIDDGGDTIMLPGEL
HELREVYNSNNTMALTGMAPAQFTPVLLGITKASLNTNSFISAASFQETT
RVLTEAAIEGKSDWLRGLKENVIIGRLIPAGTGFK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8urw Chain Z Residue 1401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8urw Cryo-EM structure of a cyanobacterial RNAP elongation complex with NusG and CTP.
Resolution2.79 Å
Binding residue
(original residue number in PDB)		C221 C302 C305
Binding residue
(residue number reindexed from 1)		C219 C300 C303
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8urw, PDBe:8urw, PDBj:8urw
PDBsum8urw
PubMed38354263
UniProtQ31N15|RPOC2_SYNE7 DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC2)

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