Structure of PDB 8gzg Chain Z Binding Site BS02

Receptor Information
>8gzg Chain Z (length=1175) Species: 1148 (Synechocystis sp. PCC 6803) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTFYNYTIDKGRLKKLIALAYRRYGSARCSQLADELKELGFRFATKAGVS
ISVDDLTIPPEKKQMLEAAEKEIRTTEERYARGEITEVERFQKVIDTWNG
TSEELKDQVVVNFRKTDPLNSVYMMAFSGARGNMSQVRQLVGMRGLMADP
QGEIIDLPIKTNFREGLTVTEYVISSYGARKGLVDTALRTADSGYLTRRL
VDVSQDVIVREQDCGTERSLRVTAMTDGDQVKISLADRLFGRLLAKDVVG
PDGEIIAKRNDEIDEALANRIAAVTDEVYVRSPLTCEAARSVCQNCYGWS
LAHGHKVDLGEAVGIIAAQSIGEPGTQLTVARQEKAPEDGTVKWGKGLST
RKVRTRHGEDAEQVEIAGDLIWKGEGKKQTYSLTPGSLLFVQDGQTVTAG
QLMTEISLTERATKDVAGDLAGEVLFDRLVPEEKTDRQGNTTRIAQRGGL
VWILSGEVYNLPPGAEPVVKNDEQVEVGSIMAETKLVTNDGGVVRLVSNR
EIEIITASVLLDQAQVKLESSGGREQYVIYTADKQRFLLKAAPGTKVQNH
SIVAELIDDRYRTTTGGMIRYAGVEVAKGGRKQGYEVTKGGTLLWIPEET
HEINKDISLLIVEDGQYVEAGTEVVKDIFCQSSGIVEVVQKNDILREIII
KPGDFYQDVDPGSVKIESGQLLQPGQDVFPGVTVSTLSQAEWIESPEGGL
LLRPVEEYKVFDEPAAPSQGSQNEEGGRQIELRSVQRLFYKDGDRVKSVE
GAPLLSTQLVLEIYHLSADIELQDDEEEDCQRLQLVILESLVLRRDESDP
LGGASKTRLLVQDGDQIPPGAVVARTEIQCKEAGTVRGIKEGQESIRRVL
LERAADRLVVDLPSAPEVKPGQLLVAGQELVPGVKLEESGKVLEIYQLVL
RRARPYRVSPGAVLHIEDGDLVQRGDNLVLLVFERVQGLPRIEELLEARK
PKEACVLARAPGVCQVEESVDIKVVEDDGTVSEYPLLPGQNAMVTDGQRI
DVGHALTDGYNNPHEILDVFFSYYVDKDGCYQAALRGLQAAQKFLVNEVQ
TVYQSQGVDISDKHIEVIVRQMTAKVRIDDGGDTTMLPGELVELRQVEQV
NEAMGITGSAARYTPVLLGITKASLNTDSFISAASFQETTRVLTEAAIEG
KSDWLRGLKENVIIGRLIPAGTGFS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8gzg Chain Z Residue 2001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8gzg Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
Resolution3.13 Å
Binding residue
(original residue number in PDB)		C214 C293 C296
Binding residue
(residue number reindexed from 1)		C214 C293 C296
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8gzg, PDBe:8gzg, PDBj:8gzg
PDBsum8gzg
PubMed
UniProtP73334|RPOC2_SYNY3 DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC2)

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