Structure of PDB 7f0d Chain Z Binding Site BS02

Receptor Information
>7f0d Chain Z (length=59) Species: 419947 (Mycobacterium tuberculosis H37Ra) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQLKITQVRSTIGARWKQRESLRTLGLRRIRHSVIREDNAATRGLIAVVR
HLVEVEPAQ
Ligand information
>7f0d Chain B (length=115) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuacggcggccacagcggcagggaaacgcccggucccauuccgaacccgg
aagcuaagccugccagcgccgaugauacugccccuccggguggaaaagua
ggacaccgccgaaca
...<<<<<<.....<<<<<<<<.....<<<<<...............>>>
..>>....>>>>>>.>>.<<...<...<<<<<<....>>>>>>.....>.
>>...>>>>>>....
Receptor-Ligand Complex Structure
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PDB7f0d Cryo-EM structure of Mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		R16 Q19 R51 H52
Binding residue
(residue number reindexed from 1)		R15 Q18 R50 H51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7f0d, PDBe:7f0d, PDBj:7f0d
PDBsum7f0d
PubMed34935599
UniProtA5U0A8|RL30_MYCTA Large ribosomal subunit protein uL30 (Gene Name=rpmD)

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