Structure of PDB 6zvk Chain Y2 Binding Site BS02

Receptor Information

>6zvk Chain Y2 (length=169) Species: 9986 (Oryctolagus cuniculus)

ENPMRELRIRKLCLNICVGESGDRLTRAAKVLEQLTGQTPVFSKARYTVR
SFGIRRNEKIAVHCTVRGAKAEEILEKGLKVREYELRKNNFSDTGNFGFG
IQEHIDLGIKYDPSIGIYGLDFYVVLGRPGFSIADKKRRTGCIGAKHRIS
KEEAMRWFQQKYDGIILPG

Ligand information

>6zvk Chain d2 (length=120)

gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu

<<<<<<<<<....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>..
..>>>>>>>>>>>>>>>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6zvk The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
• Resolution: 3.49 Å
• Binding residue (original residue number in PDB): M12 Q46 T47 V49 T73 R75 G138 S140 I141 D143 I151 A153 K154 H155
• Binding residue (residue number reindexed from 1): M4 Q38 T39 V41 T65 R67 G130 S132 I133 D135 I143 A145 K146 H147

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6zvk, PDBe:6zvk, PDBj:6zvk
• PDBsum: 6zvk
• PubMed: 33296660
• UniProt: G1TUB8|RL11_RABIT Large ribosomal subunit protein uL5 (Gene Name=RPL11)