Structure of PDB 7oqy Chain Y Binding Site BS02

Receptor Information
>7oqy Chain Y (length=92) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRFCPKCGSFLKVKGNKMVCSKCGYSDHDVEKVILKENVAHENDKTIIAD
GETIEGRVAISLCPRCGSVRAILLNKKKRLYRCMTCNFVYNI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7oqy Chain Y Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7oqy Structural basis of RNA polymerase inhibition by viral and host factors.
Resolution2.61 Å
Binding residue
(original residue number in PDB)		C63 C66 C83
Binding residue
(residue number reindexed from 1)		C63 C66 C83
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0051607 defense response to virus
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7oqy, PDBe:7oqy, PDBj:7oqy
PDBsum7oqy
PubMed34535646
UniProtQ97X43|TFS4_SACS2 Transcription factor S4 (Gene Name=tfs4)

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