Structure of PDB 5zwn Chain Y Binding Site BS02

Receptor Information
>5zwn Chain Y (length=196) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSTPAAEQRKLVEQLMGPKICKSYLVGECPYDLFQGTKQSLGKCPQMHLT
KHKIQYEREVKQGKTFPEFEREYLAILSRFVNECNGQISVALQNLKHTAE
ERMKIQQVTEELDVLDVRIGLMKLQELISKRKEVAKRVRNITENVGQSAQ
QKLQVCEVCGAYLSRLDTDRRLADHFLGKIHLGYVKMREDYDRLMK
Ligand information
>5zwn Chain P (length=480) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auacuuaccuuaagauaucagaggaaaguccuacugaucaaacaugcgcu
uccaauaguagaaggacguuaagcauuuaucauugaacuaguucauugaa
gucauugaugcaaacuccuuggucacacacacggcgcggaaggcguguuu
gcugacguuuccauucccuuguuucaaucauugguuaaucccuuuggguu
aaacugauuuuuggggcccuuuguuucuucugccuggagaaguuugacac
caaauucaaauugguguuaggggagcuggggccuuucaaaagagcuuugu
agaggcauucuuuuugacuacuuuucgcgugccauuuuaguuuuugacga
uucgaaugaacuaguuuaugaugaaguugagauuauuuggucgauuguag
uuugaagauguagucucaacuuugcucaaauuuuggaaggucuugguagg
aacggguggaucuuauaauuuuugauuuau
...........<<<<.<<<<<<<<.....>>>.>>>>><<<<<<<<<.<<
<<<........<<<<<.<<<..<<<<.<.<<<.<<<<<..>>>>>.>>>.
......>>>>>.>>>>>>>>.................>>>>>>>>>>>>>
><<<.<<<<.<<..<<<<<.<<<<<<<..<<<<<<<.<.<<<...>>>.>
.>>>>>>>..>>>>>>>((.......<<<<<....))>>>>>...<<<<<
<<<.......>>>>>>>>.>>>>><<<<<<<<<<<<<<<<<..<<...<<
.<<<<<..<<<<<..<<<<<<..<<.....<<<<...<<<<<<..<<<..
<<<<.<<<<<<<>>>>>>>..>>>>>>>.>>>>>>..>>>>.>>..>>>>
>>.>>>>>....>>>>>.>>...>>.....>>>>>>>>>>>>>>>>>.>>
>>>>..>>>.>>>>................
Receptor-Ligand Complex Structure
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PDB5zwn Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation
Resolution3.4 Å
Binding residue
(original residue number in PDB)
S5 T6 Y207 R216 D219 H220 K224
Binding residue
(residue number reindexed from 1)
S2 T3 Y162 R171 D174 H175 K179
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006376 mRNA splice site recognition
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0005829 cytosol
GO:0071004 U2-type prespliceosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5zwn, PDBe:5zwn, PDBj:5zwn
PDBsum5zwn
PubMed29794219
UniProtQ07508|LUC7_YEAST Protein LUC7 (Gene Name=LUC7)

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