Structure of PDB 3ccl Chain Y Binding Site BS02

Receptor Information
>3ccl Chain Y (length=142) Species: 2238 (Haloarcula marismortui) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TELQARGLTEKTPDLSDEDARLLTQRHRVGKPQFNRQDHHKKKRVSTSWR
KPRGQLSKQRRGIKGKGDTVEAGFRSPTAVRGKHPSGFEEVRVHNVDDLE
GVDGDTEAVRIASKVGARKRERIEEEAEDAGIRVLNPTYVEV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3ccl Chain Y Residue 8086 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3ccl Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		H133 K136 K137 V139
Binding residue
(residue number reindexed from 1)		H39 K42 K43 V45
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006281 DNA repair
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3ccl, PDBe:3ccl, PDBj:3ccl
PDBsum3ccl
PubMed18455733
UniProtP12736|RL32_HALMA Large ribosomal subunit protein eL32 (Gene Name=rpl32e)

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