Structure of PDB 2iy4 Chain Y Binding Site BS02

Receptor Information

>2iy4 Chain Y (length=150) Species: 1639 (Listeria monocytogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VDTKEFLNHQVANLNVFTVKIHQIHWYMRGHNFFTLHEKMDDLYSEFGEQ
MDEVAERLLAIGGSPFSTLKEFLENASVEEAPYTKPKTMDQLMEDLVGTL
ELLRDEYQQGIELTDKEGDNVTNDMLIAFKASIDKHIWMFKAFLGKAPLE

Ligand information

Ligand ID

InChI

InChI=1S/Fe/q+3

InChIKey

VTLYFUHAOXGGBS-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Fe+3]

Formula

Name

FE (III) ION

PDB chain

2iy4 Chain Y Residue 1157 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	2iy4 The Mutations Lys 114 --> Gln and Asp 126 --> Asn Disrupt an Intersubunit Salt Bridge and Convert Listeria Innocua Dps Into its Natural Mutant Listeria Monocytogenes Dps. Effects on Protein Stability at Low Ph.
Resolution	2.31 Å
Binding residue (original residue number in PDB)	D58 E62
Binding residue (residue number reindexed from 1)	D52 E56
Annotation score	5

Enzymatic activity

Enzyme Commision number

1.16.-.-

Gene Ontology

	Molecular Function
GO:0008199	ferric iron binding
GO:0016491	oxidoreductase activity
GO:0016722	oxidoreductase activity, acting on metal ions
GO:0046872	metal ion binding

	Biological Process
GO:0006879	intracellular iron ion homeostasis

	Cellular Component
GO:0005737	cytoplasm

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:2iy4, PDBe:2iy4, PDBj:2iy4
PDBsum	2iy4
PubMed	17186524
UniProt	Q8Y8G1\|DPS_LISMO DNA protection during starvation protein (Gene Name=dps)

[Back to BioLiP]