Structure of PDB 1yjn Chain Y Binding Site BS02

Receptor Information

>1yjn Chain Y (length=142) Species: 2238 (Haloarcula marismortui) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TELQARGLTEKTPDLSDEDARLLTQRHRVGKPQFNRQDHHKKKRVSTSWR
KPRGQLSKQRRGIKGKGDTVEAGFRSPTAVRGKHPSGFEEVRVHNVDDLE
GVDGDTEAVRIASKVGARKRERIEEEAEDAGIRVLNPTYVEV

Ligand information

InChI=1S/Mg/q+2

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Mg

Name

MAGNESIUM ION

PDB chain

1yjn Chain Y Residue 8108 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	1yjn Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Resolution	3.0 Å
Binding residue (original residue number in PDB)	H133 K136 K137 V139
Binding residue (residue number reindexed from 1)	H39 K42 K43 V45
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding

	Biological Process
GO:0006281	DNA repair
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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External links

PDB	RCSB:1yjn, PDBe:1yjn, PDBj:1yjn
PDBsum	1yjn
PubMed	15851032
UniProt	P12736\|RL32_HALMA Large ribosomal subunit protein eL32 (Gene Name=rpl32e)

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