Structure of PDB 6zsd Chain XM Binding Site BS02

Receptor Information
>6zsd Chain XM (length=287) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARALDLLRGLPRVSLANLKPNPGSKKPERRPRGRRRGRKCGRGHKGERQR
GTRPRLGFEGGQTPFYIRIPKYGFNEGHSFRRQYKPLSLNRLQYLIDLGR
VDPSQPIDLTQLVNGRGVTIQPLKRDYGVQLVEEGADTFTAKVNIEVQLA
SELAIAAIEKNGGVVTTAFYDPRSLDIVCKPVPFFLRGQPIPKRMLPPEE
LVPYYTDAKNRGYLADPAKFPEARLELARKYGYILPDITKDELFKMLCTR
KDPRQIFFGLAPGWVVNMADKKILKPTDENLLKYYTS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6zsd Chain XM Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6zsd Structural basis of mitochondrial translation.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
G42 R43 R44 R45 G46
Binding residue
(residue number reindexed from 1)
G33 R34 R35 R36 G37
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
GO:1990830 cellular response to leukemia inhibitory factor
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6zsd, PDBe:6zsd, PDBj:6zsd
PDBsum6zsd
PubMed32812867
UniProtQ9P015|RM15_HUMAN Large ribosomal subunit protein uL15m (Gene Name=MRPL15)

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