Structure of PDB 7aoi Chain XC Binding Site BS02

Receptor Information
>7aoi Chain XC (length=584) Species: 5691 (Trypanosoma brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKVSSRGPIVRWALSRPTSGLVSSPSEWRCGRDLSDEEKHSGLLLRIRDI
CQPLAKNDQLPVAVVKAQPSDLQVNEVDAVGDVAALSKVVKGKWRKISRQ
KTLLIEDDARTPFSDPSKSFSPRVQSYGEYVRLTGKLPRDLPVLRFVLYR
DSYSLNSVENRLGYVLSLQPDCVFLRDQPGGSFGCITQHGVCLGVTKEIL
SHASRHYNLHPLIFEPREYFSTDKLHSLLQGARGHHHRVLLRCVEGSQDT
IRALLKKTAERGFINYFWLDRFSVGTNRFFDMAVLAARGDYLKSIGALLH
CVAESNGVHYDHFLKYLNADPSTVPGIAQTWATTAKHMRSPNWIVQLLRG
LHKYHADAECGKSSYLAELWSALPMREALRRSAAEFVWNAMASQRLLSKG
LNVVEGDVVRMTFKITDVVLPVPYGSVAANNCLFPHLSPLDKKLYVEFAT
KHGMSFLFDEQMPSPLSNPLQFYRHLITKPVNMQVSVIRDPNSLTSIKSD
LAVMQERKLVQIGDIDYSTRVREPCVYNVSERFTEKMEEILKTHRGPNSV
VLSCYLPEDSSPFVMLREVFDLRHASFHDLYGLL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7aoi Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R6 L285 Q394 H484
Binding residue
(residue number reindexed from 1)		R6 L285 Q394 H452
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0009982 pseudouridine synthase activity
GO:0016853 isomerase activity
Biological Process
GO:0001522 pseudouridine synthesis
GO:0009451 RNA modification
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7aoi, PDBe:7aoi, PDBj:7aoi
PDBsum7aoi
PubMed33576519
UniProtD0A7A5

[Back to BioLiP]