Structure of PDB 8qpe Chain X Binding Site BS02

Receptor Information
>8qpe Chain X (length=80) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DYWKSQPKKFCDYCKCWIADNRPSVEFHERGKNHKENVAKRISEIKQKSL
DKAKEEEKASKEFAAMEAAALKAYQEDLKR
Ligand information
Receptor-Ligand Complex Structure
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PDB8qpe Structural insights into the cross-exon to cross-intron spliceosome switch
Resolution3.1 Å
Binding residue
(original residue number in PDB)		H30 G33 K34
Binding residue
(residue number reindexed from 1)		H28 G31 K32
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0070064 proline-rich region binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0045292 mRNA cis splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0016607 nuclear speck
GO:0071005 U2-type precatalytic spliceosome
GO:0071011 precatalytic spliceosome

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Cellular Component
External links
PDB RCSB:8qpe, PDBe:8qpe, PDBj:8qpe
PDBsum8qpe
PubMed38778104
UniProtO75554|WBP4_HUMAN WW domain-binding protein 4 (Gene Name=WBP4)

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