Structure of PDB 7sfr Chain X Binding Site BS02

Receptor Information
>7sfr Chain X (length=63) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAAVCDICGKGPGFGKSVSHSHRRTSRRWDPNIQTVHAVTRPGGNKKRLN
VCTSCIKAGKITR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7sfr Chain X Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7sfr Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
C5 C8 C55
Binding residue
(residue number reindexed from 1)
C5 C8 C55
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7sfr, PDBe:7sfr, PDBj:7sfr
PDBsum7sfr
PubMed36827973
UniProtP0DV54|RL28C_MYCTU Large ribosomal subunit protein bL28C (Gene Name=rpmB3)

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