Structure of PDB 7qwr Chain X Binding Site BS02

Receptor Information
>7qwr Chain X (length=119) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAM
KKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAY
VRLAPDYDALDVANKIGII
Ligand information
>7qwr Chain 8 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<<..>>><<<<<<<<.......>>>>>>>>..............
......
Receptor-Ligand Complex Structure
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PDB7qwr Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
P49 L52 R56 K63 P66 R67 R68 K70 N105 H107 Q108
Binding residue
(residue number reindexed from 1)
P12 L15 R19 K26 P29 R30 R31 K33 N68 H70 Q71
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7qwr, PDBe:7qwr, PDBj:7qwr
PDBsum7qwr
PubMed35201867
UniProtG1SE76|RL23A_RABIT Large ribosomal subunit protein uL23 (Gene Name=RPL23A)

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