Structure of PDB 7pnw Chain X Binding Site BS02

Receptor Information
>7pnw Chain X (length=357) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AERPRTVSRTSDSDPAKHGEQHEGQHYSIPLQDLKTVFPHGLPPRYMMQV
KTFGEACLMVRKPALELLGYLKNTNFAHPAVRYLLYGEKGTGKTLSLCHA
VHFCARHDWLILHIPDAHLWVKNCRELLQSTHNKQRFDQPLEASTWLKNF
KTTNERFLSQIKVQEKYVWNKRESTEKGSPLGEVVEQGLTRVRNATDAVG
VVLKELKAQSALGLFHLLVAVDGVNALWGRTTLKKEDRTLIAPEELSLVH
NLRKMVKNDWHGGAIVLSLSQTGSLFKSRTAYLPHELLGKEGFNALEPFL
PILIPNYNPKEFESSFQYYLENNWLQHEKASTEEGRKELRFLSNCNPEQL
ERLCASL
Ligand information
Ligand IDATP
InChIInChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyZKHQWZAMYRWXGA-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
FormulaC10 H16 N5 O13 P3
NameADENOSINE-5'-TRIPHOSPHATE
ChEMBLCHEMBL14249
DrugBankDB00171
ZINCZINC000004261765
PDB chain7pnw Chain X Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pnw Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Resolution3.09 Å
Binding residue
(original residue number in PDB)		P77 L92 M93 G126 K127 T128 L129 T306 P381 E382 E385
Binding residue
(residue number reindexed from 1)		P43 L58 M59 G92 K93 T94 L95 T272 P347 E348 E351
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006915 apoptotic process
GO:0008637 apoptotic mitochondrial changes
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005761 mitochondrial ribosome
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7pnw, PDBe:7pnw, PDBj:7pnw
PDBsum7pnw
PubMed35676484
UniProtQ9ER88|RT29_MOUSE Small ribosomal subunit protein mS29 (Gene Name=Dap3)

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